Friday, May 22, 2020

Steroids Abuse in Baseball - 1746 Words

Steroid Abuse Hurts Baseball The abuse of steroids among players in Major League Baseball is corrupting the image of Americas Pastime as well as endangering the health of those who use the illegal substances. The lack of testing and punishment for the use of illegal substances like steroids in the Major Leagues portrays a negative image to aspiring young athletes. They see their role models using steroids and becoming better athletes rather than seeing suspensions for the illegal behavior or the negative health effects. Anabolic-androgenic steroids are synthetic substances which increase skeletal muscle growth and increase male hormone production. Steroids are legal only through prescription. They are often prescribed for ailments†¦show more content†¦In fact, the details of the new policy reveal that the penalty for a first offense can be either a suspension or a fine of $10,000 or less; that there is no public identification of players who are fined instead of suspende d; and that even if players are suspended, the public disclosure is limited to the fact of their suspension with no official confirmation that the player tested positive for steroids (Davis, np). The committee also questions the leagues decision for who supervises the drug testing: Under the new Major League Baseball policy, many key implementation decisionsÂ… are to be made by a four-person committee that includes Robert D. Manfred, Jr., Major League Baseballs Executive Vice President, Labor and Human Resources, and Gene Orza, the Chief Operating Officer and Associate General Counsel of the Major League Players Association. According to the policy, some of these decisions must be made unanimously, giving both Major League Baseball management and the players union a veto (Davis, np). Another question brought up in the letter is the Anti-Oversight Clause: The new policy contains an extraordinary provision that in the event of a governmental investigation relating to drug testing of players, all testing Â… shall be suspended immediately. The suspension will remain in effect until the government investigation is withdrawn, the league and players union have successfully resisted an investigation at the trial court level, or bothShow MoreRelated Steroid Abuse Hurts Baseball Essay1701 Words   |  7 PagesSteroid Abuse Hurts Baseball   Ã‚  Ã‚  Ã‚  Ã‚  The abuse of steroids among players in Major League Baseball is corrupting the image of America?s Pastime as well as endangering the health of those who use the illegal substances. The lack of testing and punishment for the use of illegal substances like steroids in the Major Leagues portrays a negative image to aspiring young athletes. They see their role models using steroids and becoming better athletes rather than seeing suspensions for the illegal behaviorRead More Steriods in sports Essay1301 Words   |  6 Pages Steroids in Sports nbsp;nbsp;nbsp;nbsp;nbsp;In my opinion, the initial reason a person starts to play any sport is to either to have fun or mainly to emulate their favorite sports figures. So many kids want to swing a bat like Barry Bonds, or rush the football like Jamal Lewis, or play soccer like Pelle’. When I was younger, I wanted to tackle like Lawrence Taylor. Since these children like to do what they see their role models do, what happens if they find out that their favorite person boostsRead MoreEssay on The Epidemic of Steroid Abuse in America1711 Words   |  7 PagesThe Epidemic of Steroid Abuse in America We as a people are preoccupied with the notion of greatness. Our role models are athletes, actors and actresses, and other figures in the public eye. Many of us often desire to be better off than our current state; to look better, to be in better shape, etc†¦ We compete with each other for jobs, for mates, for grades, for parking spots, and in sporting activities. This competitive nature is a way of life, especially in sporting activities, often learnedRead MoreSteroids in the World of Athletes and Sports1603 Words   |  6 PagesIntroduction Steroids are a hot topic of debate and controversy in the world of athletes and sports. Steroids fall under the umbrella of performance enhancing drugs (PEDs) and are a dark cloud that have been hovering over the sports world for a long time. In the world today, steroids are the most relevant in major league baseball. Many baseball players, such as Barry Bonds, Alex Rodriguez, Ryan Braun, and Mark McGwire, just to name a few, have ruined their reputations because of steroids. There areRead MoreSteroids : Steroids And Steroids1425 Words   |  6 Pages Steroids in Baseball Players like Barry Bonds, Sammy Sosa, Roger Clemens, Mark McGwire and Alex Rodriguez, just to name a few, have disobeyed the game of baseball, and for what? To add an extra 2-5 mph on their fastball, or to hit the ball farther. If scouts liked you when you weren’t on steroids, why would you need to go on to them. It totally takes out your natural ability of what made you the baseball player that scouts recruited you. This isn’tRead MoreAnabolic Steroids : A Fatal Attraction1734 Words   |  7 PagesAnabolic Steroids in Sports The market for top performing athletes in sports in the 21st century is a competitive one. Athletes are pushed to, be stronger, an heal from injuries faster. With the pressure to do well and get picked up by a professional team of sorts goes without saying that hard work is a must to elevate ones professional athletic career, but what if one has reached a plateau or hit a wall in a training regimen and just can not seem to push through? When some athletes hit the proverbialRead MoreEffects Of Performance Enhancing Drug Usage In Sports1056 Words   |  5 Pagesduring the usage of steroids advertised by the sports athletes. Professional athletes, such as baseball players, have been in the spotlight, especially during their season and the Olympics. In season athletes are the ones that use steroids the most to enhance their performance. Teenagers in high school also admit to have used anabolic steroids at some point of their life. After all, non medical use of steroids is illegal, amen dments have been advanced in the anabolic steroid control arrangementsRead MorePED in Sports Essay1644 Words   |  7 Pagesthe honesty of the game, but also can have broader social affects that one may not even realize. The use of performance enhancing drugs is especially apparent in Major League Baseball. This problem can be traced back to the 1980’s when baseball was facing one of its first â€Å"dark periods†. During the 1980’s Major League Baseball was experiencing a home run drought. Home run totals were down as far as they had been since Babe Ruth, and fans were seemingly becoming bored with the sport. The lack of homeRead More A Baseball Proposal Essay1574 Words   |  7 PagesA Baseball Proposal Ever since the creation of Americas favorite pastime, baseball, cheating has been an integral part of the game. Each era of baseball has offered new and improved techniques for cheating the game of baseball. Cheating has become a common occurrence in baseball, from the 1919 Chicago BlackRead MoreEssay about Media Sports: How did Baseball get Affected by Steroids?1246 Words   |  5 Pagesways. This can be seen in America’s national pastime baseball. Baseball is a sport that became the national sport in the United States in the late 19th century. From the beginning of the sport they tried to keep the highest standards to each player and ball club. There were times of scandal, but of all the things that happen to baseball substance abuse has been portrayed as one of the worst thing a player could do. To defame the baseball was to ruin everything the sport stood for. This research

Friday, May 8, 2020

Freedom of Speech The Engel Vs Vitale Case Essay example

Freedom of speech was a big topic spoken about in the 1950’s and even today. Schools in the 1950’s had to recite a specific prayer every morning in school not like today. Students had to recite the â€Å"twenty two word regents prayer†. The Engel Vs Vitale case has to do with separation of church and state, meaning that there should be a separation between peoples views on religious freedom and the government. In the first amendment, Thomas Jefferson introduced this law and rule during the colonies but then this later evolved into the United States, where into the 1950’s became a huge debate on who was right and who was wrong. The Supreme Court case Engel v. Vitale expanded the rights of Americans because the Supreme Court ruled in favor of†¦show more content†¦Petitions were filed and New York State upheld the case and then sent it to the Supreme Court(Britannica School High paragraph 2). A couple of the families were Jewish, another family was atheist, one parent was Unitarian and the last parent was of an ethical culture society. The Parents were to believe that the school was violating the first amendment of the constitution and this was not right; that according to Thomas Jefferson there should be a separation of state and church. Never before had the public school board been argued against with prayer like issues ( Haas, pg 7-20). The Supreme court case started in 1959 and ended in 1962, surprising the whole nation. One of the most historic most remembered cases was announced on June 25th, 1962 giving a lot of people anxiety and releasing a lot of stress. The voting came out to six votes to one vote in favor of Engel and the students ending the eight second prayer called the â€Å"Regents Prayer†. 2 votes were unsolicited, because Justice Byron R. White was a new Justice and did not think it was right to vote right on admittance to the system. The other vote was not taken by Justice Felix Frankfurter because he was about to retire, due to old age andShow MoreRelatedIntent of the Framers1628 Words   |  7 Pagesintent of the freedom of speech, freedom of religion, right to privacy, and criminals’ rights. I will explain current views of the provisions of freedom of speech, freedom of religion, right to privacy, and criminals’ rights. I will assess which events and opinions have changed the intent of each of these provisions over time. I will evaluate the effects of Supreme C ourt decisions related to these provisions and express consideration for the future of these provisions. Freedom of speech is part ofRead MoreUs Bill of Rights First Amendment1740 Words   |  7 PagesU.S. Supreme Court Cases that challenged the â€Å"First Amendment.† The â€Å"First Amendment† includes the Right to Choose Ones Religion, and does not allow the government to create any laws in respect to establishing a religion. The â€Å"First Amendment† also includes the rights to, Freedom of Speech, Freedom of the Press, Right to Assemble and Petition the Government to address Citizen’s Grievances. Here is a summary of three important and controversial â€Å"U.S. Supreme Court Cases.† All of which posedRead MoreThe Civil Liberties Of The United States Essay1513 Words   |  7 PagesCivil liberties is the individual rights and freedoms that government is obliged to protect, normally by not interfering in the exercise of these rights and freedoms. However, over the years the rights for the people have either have become open and free or it has become restrictive. The bill of rights in terms of scope in civil liberties protection has changed by three paths such three paths are increased in authority of federal government, the Supreme court shifted its interpretation of constitutionalRead More1st and 2nd Amendment1723 Words   |  7 Pagesï » ¿ The First and Second Amendments of the United States Constitution On September 25, 1789, The Bill Of Rights was submitted to the states for approval, based on the previous Constitutions insufficient assurances for civil freedom, liberties and justice. Concerned that the Constitution neglected to clearly state the basic civil rights of the citizens of the United States, Anti- Federalists opposed the Articles of Confederations, which gave state governments more authority (â€Å"Bill of Rights, n.dRead MorePrayer in Public Schools894 Words   |  4 Pagesdifficult to bring forth any kind of change that will bridge the gap between school and religion. There have been several attempts over the years to use the power of the first amendment of the United States constitution which expresses the right to freedom of speech and religion to justify prayer in schools. Although the first amendment clearly sets out to protect religion from government intervention, the U.S Supreme court has ruled prayer in public school â€Å"unconstitutional† because it violates the separationRead MoreThe First Ammendment and Dealing with the Separation of Church and State1741 Words   |  7 Pagespersonal freedoms in the United States has been significantly important (Klinker, 1991: 109). The original Constitution did not contain a bill of rights because the convention delegates felt that individual rights were in no danger and would be protected by the states. However, the lack of a bill of rights was the strongest objection to the ratification of the Constitution (Klinker:109-110). Even in the early stages of American history there was an urge to put legally protected freedoms into writtenRead MoreAp Government Chapter 15 Study Guide1893 Words   |  8 Pagesreferred to as â€Å"negative rights†) are freedoms that are guaranteed to an individual. These are restraints on the gov. Civil liberties declare what the government cannot do. d. Civil rights (â€Å"positive rights†) are powers and privileges that are guaranteed to the individual and protected against arbitrary removal at the hands of the gov or individuals. Like the right to vote or free expression and stuff. 3. The First Amendment guarantees freedom of religion in two clauses: e. TheRead More Prayer in Public School Essay3032 Words   |  13 Pagesschool, despite the fact that prayer is actually substantial. The First Amendment of the U.S Constitution states Congress shall make no law respecting an establishment of religion, or prohibiting the free exercise thereof; or abridging the freedom of speech, or of the press, or the right of the people peaceably to assemble, and to petition the government for the redress of grievances (Greenberg). This first amendment protects both believers and nonbelievers from government interference in theirRead MoreThe Supreme Law Of The Land1989 Words   |  8 Pagesor original understanding of its provisions, betray the rule of law and make a mockery of their oath of fidelity to the Constitution. Justice Scalia was the epitome of an originalist. He was known for his colorful but bold dissenting opinions in cases which usually included a debate about inalienable rights. As mention earlier Scalia believed many judges gave citizens rights which they were not granted by the United States Constitution. For example: Roe v. Wade, the Court ruled in a majori ty opinionRead MoreThe Separate But Equal Doctrine Is Plessy V. Ferguson Essay2095 Words   |  9 Pagesthe American society were that (1) schools were segregated,(2) the whites finally accepted the equality of African Americans, (3) the American society was changed forever after this case, (4) the whole U.S. acts differently towards cases that involve mixed genders now, and (5) Strict laws were changed because of this case. B. Separate but equal was a legal doctrine in United States constitutional law according to which racial segregation did not violate the Fourteenth Amendment to the United States

Wednesday, May 6, 2020

The inflammatory phases of Atherosclerosis Free Essays

Abstract Aim – This review describes recent investigations in to the impact of atherosclerosis on the vessel using four inflammatory stages eventually leading to cardiovascular complication. Research in to atherosclerosis has intensified globally as it has become one of the main reasons for increased mortality among individuals particularly within western societies. Inflammation has been established as the principal concept due to it stimulating progressive lesion development. We will write a custom essay sample on The inflammatory phases of Atherosclerosis or any similar topic only for you Order Now As a result it is known as a chronic inflammatory disorder. Numerous cellular and molecular inflammatory mediators participate in the formation, development and rupture of the atherosclerotic plaque. Several experimental studies have demonstrated that monocyte- derived macrophages as well as T-lymphocytes are the most distinctive cells to accumulate within progressive plaques and induce the production of pro-inflammatory components, more recently, potential anti-inflammatory mediators have been identified in the inflammatory response. The rate of progressive plaque development varies in different types of people. Risk factors increase the development of this condition and promote the occurrence of physical symptoms on the patient. Conclusions – (1) Inflammation attacks arteries systematically within phases and (2) the significance of the role of inflammatory molecules, linking inflammation to atherosclerosis. Introduction The management of cardiovascular diseases has significantly improved, however it is still not clearly understood as to why atherosclerosis remains the leading pathological cause of both morbidity and mortality in developed countries. Atherosclerosis is known to be a type of arteriosclerosis, but in addition to the hardening and narrowing of the arteries, cholesterol begins to deposit within their walls. It is a multifactorial disease which includes build up of atheromatous plaque and accumulation of more complex lesions within the arterial walls specifically in the intimal layer leading to the rupture of these vulnerable atherosclerotic plaques (Skjot-Arkil et al, 2010). This process is initiated in childhood and according to the results of PDAY (pathobiological determinants of atherosclerosis in youth study), visible symptoms of atherosclerosis will occur between ages of 15-54 years (McGill et al.2007). Furthermore this disease can occur in both medium and large sized arteries including the aorta, carotid artery and even the smaller coronary arteries. Due to the fact that it affects multiple arterial locations, it can then lead to clinical diseases such as coronary artery disease, cerebrovascular disease, myocardial infarction. Jongstra et al. (2006) demonstrated that within the intima of VCAM-1 positive mice, local chronic inflammation predisposed to atherosclerosis. This provided further evidence to support previous studies that inflammation participates in the atherosclerotic process. Consequently, inflammation is progressively involved in the plaque formation, resulting in an inevitable stenosis (Vidal-Vanaclocha, 2009). Numerous epidemiological studies have revealed many risk factors that accelerate atherosclerosis development including age, male gender, obesity, smoking, hypertension and diabetes mellitus. Moreover, a recent study (Holvoet et al, 2007) found that a positive correlation exists between an increased amount of oxidised LDL and the quantity of calcium built up in the coronary artery. Therefore showing that increased amount of oxidised LDL is a unique risk factor for the development of atherosclerosis. The factors that facilitate this plaque formation are inflammatory mediators. As the endothelial cell is activated, this results in expression of many cell surface adhesion molecules including cytokines, chemokines, monocytes, immunoglobulins. These promote endothelial dysfunction in atherosclerosis as well as inducing foam cell formation with the assistance of macrophages. However, the functional mechanisms of cytokines in initiating and prolonging atherosclerosis are still not clearly un derstood. Aims To explore the role of inflammation in atherosclerosis To explore the mechanisms of inflammatory cell recruitment and accumulation within the plaque. To explore the function of various different mediators in this process, including both pro and anti-inflammatory mediators. Rationale of the aims To investigate the effects of the inflammatory cycle on arteries using atherosclerosis as the central condition. Hence, following the aims and objectives of the literature review, an overview of numerous meta-analyses of mediator involvement in this process is provided. This would be performed by reviewing the most relevant literature for the past five years using Pubmed, Science direct and Google Scholar. Table 1 Methodical reviews on the involvement of inflammatory components within the development of atherosclerosis. Type of componentMediatorExperimental sourceInflammatory effectEffect on AtherosclerosisAuthor, year ImmunoglobulinICAM-1Human plasma Human aortic SMC Human aortic endothelial cells^ ^ ^ ^ ^ ^ Bielinski et al, 2008 Burton et al, 2009 Roth et al, 2007 ImmunoglobulinVCAM-1Human plasma Human aortic endothelial cells^ ^ ^ ^ Bielinski et al, 2008 Roth et al, 2007 CytokineTNF-alphaAPoE-/- micev v Bhaskar et el, 2011 CytokineIFN-gammaHuman RNA^ ^ Niedzielska and Cierpka, 2010 CytokineM-CSFHuman platelets^ Siezer et al, 2010 CytokineIL-6Human aortic endothelial cells Human Plasma APoE-/- mice^ ^ v ^ ^ v Roth et al, 2007 Hoshi et al, 2008 Bhaskar et al, 2011 CytokineIL-1 (beta)Human aortic SMC APoE-/- mice ^ ^ ^ ^ Burton et al, 2009 Bhaskar et al, 2011 ChemokineCXCL16Human and murine macrophages APoE-/-^ ^ ^ Lehrke et al, 2007 Wen-Yi et al, 2011 ChemokineCXCR6Human and murine macrophages^ ^ Lehrke et al, 2007 LigandCD40 LHuman umbilical vein endothelial cells^ ^ Chakrabarti et al, 2010 Monocyte ProteinMCP-1Human aortic endothelial cellsAPoE-/- mice^ v ^ v Roth et al, 2007 Bhaskar et al, 2011 Toll-like receptorTLR-2^ Doherty et al, 2006 How to cite The inflammatory phases of Atherosclerosis, Essay examples